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What is berberine, the supplement dubbed 'nature's Ozempic' on social media?
A dietary supplement called berberine is gaining momentum on social media for its weight loss effects,even being referred to by some as “nature’s Ozempic,” in reference to the popular drug that can helppeople shed pounds.
Users say berberine, which is found in a number of plants, including barberry plants, helps curb appetiteand improve blood sugar levels, resulting in weight loss. Google searches for “berberine” began toincrease at the end of March before they spiked in late May.

Nature' s Ozempic: A Look Into the Supplement Berberine
As the frenzy over Ozempic, Mounjaro, and other incretin-based weight-loss prescriptions continues, a herbal supplement known as berberine has gone viral on TikTok, with devotees calling it nature’s Ozempic.

Health Benefits of Berberine
Health Benefits of Berberine
By Sarah Garone
Updated on May 26, 2024
Medically reviewed by
Kristie Reed, PharmD
Fact checked by
Nick Blackmer
A supplement called berberine has trended as a "natural" version of Ozempic (semaglutide). Some people claim that taking berberine can help with weight loss and blood glucose (sugar) management. Research has shown that berberine may promote weight loss, but more clinical studies are needed.1